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Unexpected conformational variations of the human centromeric chromatin complex

We combined classical salt fractionation with chromatin immunoprecipitation to recover human centromeric chromatin under native conditions. We found that >85% of the total centromeric chromatin is insoluble under conditions typically used for native chromatin extraction. To map both soluble and i...

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Detalles Bibliográficos
Autores principales: Thakur, Jitendra, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828391/
https://www.ncbi.nlm.nih.gov/pubmed/29386331
http://dx.doi.org/10.1101/gad.307736.117