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Widespread transcriptional pausing and elongation control at enhancers

Regulation by gene-distal enhancers is critical for cell type-specific and condition-specific patterns of gene expression. Thus, to understand the basis of gene activity in a given cell type or tissue, we must identify the precise locations of enhancers and functionally characterize their behaviors....

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Detalles Bibliográficos
Autores principales: Henriques, Telmo, Scruggs, Benjamin S., Inouye, Michiko O., Muse, Ginger W., Williams, Lucy H., Burkholder, Adam B., Lavender, Christopher A., Fargo, David C., Adelman, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828392/
https://www.ncbi.nlm.nih.gov/pubmed/29378787
http://dx.doi.org/10.1101/gad.309351.117