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The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription

Gene expression is regulated by promoters, which initiate transcription, and enhancers, which control their temporal and spatial activity. However, the discovery that mammalian enhancers also initiate transcription questions the inherent differences between enhancers and promoters. Here, we investig...

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Detalles Bibliográficos
Autores principales: Mikhaylichenko, Olga, Bondarenko, Vladyslav, Harnett, Dermot, Schor, Ignacio E., Males, Matilda, Viales, Rebecca R., Furlong, Eileen E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828394/
https://www.ncbi.nlm.nih.gov/pubmed/29378788
http://dx.doi.org/10.1101/gad.308619.117