Assessment of data transformations for model-based clustering of RNA-Seq data

Quality control, global biases, normalization, and analysis methods for RNA-Seq data are quite different than those for microarray-based studies. The assumption of normality is reasonable for microarray based gene expression data; however, RNA-Seq data tend to follow an over-dispersed Poisson or neg...

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Detalles Bibliográficos
Autores principales: Noel-MacDonnell, Janelle R., Usset, Joseph, Goode, Ellen L., Fridley, Brooke L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828440/
https://www.ncbi.nlm.nih.gov/pubmed/29485993
http://dx.doi.org/10.1371/journal.pone.0191758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828440/
https://www.ncbi.nlm.nih.gov/pubmed/29485993
http://dx.doi.org/10.1371/journal.pone.0191758

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