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Low IL-6, IL-10, and TNF-α and High IL-13 Cytokine Levels Are Associated with Severe Hepatic Fibrosis in Schistosoma mansoni Chronically Exposed Individuals

Several studies have attributed the etiopathogenesis of chronic Schistosoma mansoni related hepatic fibrosis to unregulated immune responses against trapped parasite ova in the host. However, there is limited data on immune profiles associated with varying degrees of the disease in a population unde...

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Detalles Bibliográficos
Autores principales: Mutengo, Mable M., Mduluza, Takafira, Kelly, Paul, Mwansa, James C. L., Kwenda, Geoffrey, Musonda, Patrick, Chipeta, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828471/
https://www.ncbi.nlm.nih.gov/pubmed/29610679
http://dx.doi.org/10.1155/2018/9754060