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Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis

The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...

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Detalles Bibliográficos
Autores principales: Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828476/
https://www.ncbi.nlm.nih.gov/pubmed/29599894
http://dx.doi.org/10.1155/2018/3075293