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Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis
The prevalence of Osteoarthritis (OA) is increasing because of the progressive aging and unhealthy lifestyle. These risk factors trigger OA by removing constraints that keep the tightly regulated low turnover of the extracellular matrix (ECM) of articular cartilage, the correct chondrocyte phenotype...
Autores principales: | Minguzzi, Manuela, Cetrullo, Silvia, D'Adamo, Stefania, Silvestri, Ylenia, Flamigni, Flavio, Borzì, Rosa Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828476/ https://www.ncbi.nlm.nih.gov/pubmed/29599894 http://dx.doi.org/10.1155/2018/3075293 |
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