Testosterone Diminishes Cabazitaxel Efficacy and Intratumoral Accumulation in a Prostate Cancer Xenograft Model()

Inactivation of the androgen receptor (AR) pathway by androgen deprivation therapy (ADT) is the mainstay of (metastatic) prostate cancer therapy. Ultimately, the AR pathway will be re-activated despite castrate levels of circulating androgens. Thereby, maintaining its role even in castration resista...

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Detalles Bibliográficos
Autores principales: Mout, Lisanne, de Wit, Ronald, Stuurman, Debra, Verhoef, Esther, Mathijssen, Ron, de Ridder, Corrina, Lolkema, Martijn, van Weerden, Wytske
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828553/
https://www.ncbi.nlm.nih.gov/pubmed/29276148
http://dx.doi.org/10.1016/j.ebiom.2017.12.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828553/
https://www.ncbi.nlm.nih.gov/pubmed/29276148
http://dx.doi.org/10.1016/j.ebiom.2017.12.024

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