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Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

Branched-chain amino acids (BCAAs) metabolite, 3-Hydroxyisobutyric acid (3-HIB) has been identified as a secreted mediator of endothelial cell fatty acid transport and insulin resistance (IR) using animal models. To identify if 3-HIB is a marker of human IR and future risk of developing Type 2 diabe...

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Detalles Bibliográficos
Autores principales: Mardinoglu, Adil, Gogg, Silvia, Lotta, Luca A., Stančáková, Alena, Nerstedt, Annika, Boren, Jan, Blüher, Matthias, Ferrannini, Ele, Langenberg, Claudia, Wareham, Nicholas J., Laakso, Markku, Smith, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828558/
https://www.ncbi.nlm.nih.gov/pubmed/29246479
http://dx.doi.org/10.1016/j.ebiom.2017.12.008