Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2(−/−) Lung Fibroblasts

The differential expression of two closelyassociated cyclooxygenase isozymes, COX-1 and COX-2, exhibited functions beyond eicosanoid metabolism. We hypothesized that COX-1 or COX-2 knockout lung fibroblasts may display altered protein profiles which may allow us to further differentiate the function...

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Detalles Bibliográficos
Autores principales: Dave, Mandar, Islam, Abul B.M.M.K., Jensen, Roderick V., Rostagno, Agueda, Ghiso, Jorge, Amin, Ashok R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828655/
https://www.ncbi.nlm.nih.gov/pubmed/29247872
http://dx.doi.org/10.1016/j.gpb.2017.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828655/
https://www.ncbi.nlm.nih.gov/pubmed/29247872
http://dx.doi.org/10.1016/j.gpb.2017.03.005

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