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Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2(−/−) Lung Fibroblasts
The differential expression of two closelyassociated cyclooxygenase isozymes, COX-1 and COX-2, exhibited functions beyond eicosanoid metabolism. We hypothesized that COX-1 or COX-2 knockout lung fibroblasts may display altered protein profiles which may allow us to further differentiate the function...
Autores principales: | Dave, Mandar, Islam, Abul B.M.M.K., Jensen, Roderick V., Rostagno, Agueda, Ghiso, Jorge, Amin, Ashok R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828655/ https://www.ncbi.nlm.nih.gov/pubmed/29247872 http://dx.doi.org/10.1016/j.gpb.2017.03.005 |
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