Interactome Analysis of Microtubule-targeting Agents Reveals Cytotoxicity Bases in Normal Cells

Cancer causes millions of deaths annually and microtubule-targeting agents (MTAs) are the most commonly-used anti-cancer drugs. However, the high toxicity of MTAs on normal cells raises great concern. Due to the non-selectivity of MTA targets, we analyzed the interaction network in a non-cancerous h...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Escobar, Andrés Julián, Méndez-Callejas, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828656/
https://www.ncbi.nlm.nih.gov/pubmed/29246518
http://dx.doi.org/10.1016/j.gpb.2017.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828656/
https://www.ncbi.nlm.nih.gov/pubmed/29246518
http://dx.doi.org/10.1016/j.gpb.2017.04.006

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