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Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone

Myelin, the insulating sheath around axons, supports axon function. An important question is the impact of mild myelin disruption. In the absence of the myelin protein proteolipid protein (PLP1), myelin is generated but with age, axonal function/maintenance is disrupted. Axon disruption occurs in Pl...

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Detalles Bibliográficos
Autores principales: Gould, Elizabeth A, Busquet, Nicolas, Shepherd, Douglas, Dietz, Robert M, Herson, Paco S, Simoes de Souza, Fabio M, Li, Anan, George, Nicholas M, Restrepo, Diego, Macklin, Wendy B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828668/
https://www.ncbi.nlm.nih.gov/pubmed/29436368
http://dx.doi.org/10.7554/eLife.34783