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Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia

The importance of epigenetic dysregulation to acute myeloid leukemia (AML) pathophysiology has become increasingly apparent in recent years. Epigenetic regulators, including readers, writers, and erasers, are recurrently dysregulated by way of chromosomal translocations, somatic mutations, or genomi...

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Detalles Bibliográficos
Autores principales: Sun, Younguk, Chen, Bo-Rui, Deshpande, Aniruddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829038/
https://www.ncbi.nlm.nih.gov/pubmed/29527516
http://dx.doi.org/10.3389/fonc.2018.00041