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The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future
For more than 35 years, the NOD mouse has been the primary animal model for studying autoimmune diabetes. During this time, striking similarities to the human disease have been uncovered. In both species, unusual polymorphisms in a major histocompatibility complex (MHC) class II molecule confer the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829040/ https://www.ncbi.nlm.nih.gov/pubmed/29527189 http://dx.doi.org/10.3389/fendo.2018.00051 |