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Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewis(a), Lewis(b), and sialyl Lewis(a)) and type II (H2, Lewis(x), Lewis(y), and sialyl Lewis(x)) Lewis antigens, frequently occurs on the...

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Detalles Bibliográficos
Autores principales: Blanas, Athanasios, Sahasrabudhe, Neha M., Rodríguez, Ernesto, van Kooyk, Yvette, van Vliet, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829055/
https://www.ncbi.nlm.nih.gov/pubmed/29527514
http://dx.doi.org/10.3389/fonc.2018.00039