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Meta- and cross-species analyses of insulin resistance based on gene expression datasets in human white adipose tissues
Ample evidence indicates that insulin resistance (IR) is closely related to white adipose tissue (WAT), but the underlying mechanisms of IR pathogenesis are still unclear. Using 352 microarray datasets from seven independent studies, we identified a meta-signature which comprised of 1,413 genes. Our...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829071/ https://www.ncbi.nlm.nih.gov/pubmed/29487289 http://dx.doi.org/10.1038/s41598-017-18082-7 |