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Meta- and cross-species analyses of insulin resistance based on gene expression datasets in human white adipose tissues

Ample evidence indicates that insulin resistance (IR) is closely related to white adipose tissue (WAT), but the underlying mechanisms of IR pathogenesis are still unclear. Using 352 microarray datasets from seven independent studies, we identified a meta-signature which comprised of 1,413 genes. Our...

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Detalles Bibliográficos
Autores principales: Jung, Junghyun, Kim, Go Woon, Lee, Woosuk, Mok, Changsoo, Chung, Sung Hyun, Jang, Wonhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829071/
https://www.ncbi.nlm.nih.gov/pubmed/29487289
http://dx.doi.org/10.1038/s41598-017-18082-7