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Galectin-1 enhances TNFα-induced inflammatory responses in Sertoli cells through activation of MAPK signalling

Galectin-1 (Gal-1) is a pleiotropic lectin involved in the modulation of immune responses. Using a model of rat experimental autoimmune orchitis (EAO), we investigated the role of Gal-1 in testicular inflammation. EAO is characterized by leukocytic infiltrates in the interstitium, damage of spermato...

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Detalles Bibliográficos
Autores principales: Lei, Tao, Moos, Sven, Klug, Jörg, Aslani, Ferial, Bhushan, Sudhanshu, Wahle, Eva, Fröhlich, Suada, Meinhardt, Andreas, Fijak, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829165/
https://www.ncbi.nlm.nih.gov/pubmed/29487346
http://dx.doi.org/10.1038/s41598-018-22135-w