Cargando…

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae

To investigate nuclear DNA replication enzymology in vivo, we have studied Saccharomyces cerevisiae strains containing a pol2-16 mutation that inactivates the catalytic activities of DNA polymerase ε (Pol ε). Although pol2-16 mutants survive, they present very tiny spore colonies, increased doubling...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garbacz, Marta A., Lujan, Scott A., Burkholder, Adam B., Cox, Phillip B., Wu, Qiuqin, Zhou, Zhi-Xiong, Haber, James E., Kunkel, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829166/ https://www.ncbi.nlm.nih.gov/pubmed/29487291 http://dx.doi.org/10.1038/s41467-018-03270-4

Ejemplares similares

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
por: Zhou, Zhi-Xiong, et al.
Publicado: (2019)

Role of Translesion Synthesis DNA Polymerases in DNA Replication in the Presence of a Weak DNA Polymerase δ in Saccharomyces cerevisiae
por: Zhang, Likui, et al.
Publicado: (2018)

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe–S cluster in DNA polymerase δ
por: Kiktev, Denis A, et al.
Publicado: (2021)

Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae
por: Dubarry, Marion, et al.
Publicado: (2015)

Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase ζ
por: Stone, Jana E., et al.
Publicado: (2009)

DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae
por: Giannattasio, Michele, et al.
Publicado: (2019)

Replication-Independent Endogenous DNA Double-Strand Breaks in Saccharomyces cerevisiae Model
por: Thongsroy, Jirapan, et al.
Publicado: (2013)

Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae
por: Prasai, Kanchanjunga, et al.
Publicado: (2017)

Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae
por: Hegedüs, Éva, et al.
Publicado: (2018)

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity
por: Lujan, Scott A., et al.
Publicado: (2012)

Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination
por: Cerqueira, Paula G, et al.
Publicado: (2023)

Polymerase δ replicates both strands after homologous recombination-dependent fork restart
por: Miyabe, Izumi, et al.
Publicado: (2015)

Fe-S coordination defects in the replicative DNA polymerase delta cause deleterious DNA replication in vivo and subsequent DNA damage in the yeast Saccharomyces cerevisiae
por: Chanet, Roland, et al.
Publicado: (2021)

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA
por: Fry, Rebecca C, et al.
Publicado: (2006)

DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation
por: Lormand, Justin D., et al.
Publicado: (2013)

Nuclear Mitochondrial DNA Activates Replication in Saccharomyces cerevisiae
por: Chatre, Laurent, et al.
Publicado: (2011)

Coupling DNA Replication and Spindle Function in Saccharomyces cerevisiae
por: Liakopoulos, Dimitris
Publicado: (2021)

Mechanism of strand displacement synthesis by DNA replicative polymerases
por: Manosas, Maria, et al.
Publicado: (2012)

Quantitative proteome and phosphoproteome datasets of DNA replication and mitosis in Saccharomyces cerevisiae
por: Rossio, Valentina, et al.
Publicado: (2022)

A model for the spatiotemporal organization of DNA replication in Saccharomyces cerevisiae
por: Spiesser, T. W., et al.
Publicado: (2009)

Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program
por: Gispan, Ariel, et al.
Publicado: (2014)

Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae
por: Barbari, Stephanie R., et al.
Publicado: (2018)

Mapping Meiotic Single-Strand DNA Reveals a New Landscape of DNA Double-Strand Breaks in Saccharomyces cerevisiae
por: Buhler, Cyril, et al.
Publicado: (2007)

Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae
por: Yang, Yong, et al.
Publicado: (2008)

Characteristics of replication-independent endogenous double-strand breaks in Saccharomyces cerevisiae
por: Pongpanich, Monnat, et al.
Publicado: (2014)

Post-replicative nick translation occurs on the lagging strand during prolonged depletion of DNA ligase I in Saccharomyces cerevisiae
por: Koussa, Natasha C, et al.
Publicado: (2021)

Synergism between CMG helicase and leading strand DNA polymerase at replication fork
por: Xu, Zhichun, et al.
Publicado: (2023)

Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA
por: Galletto, Roberto, et al.
Publicado: (2013)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
por: Hirota, Kouji, et al.
Publicado: (2016)

Plant DNA polymerases α and δ mediate replication of geminiviruses
por: Wu, Mengshi, et al.
Publicado: (2021)

Correction: Mapping Meiotic Single-Strand DNA Reveals a New Landscape of DNA Double-Strand Breaks in Saccharomyces cerevisiae
por: Buhler, Cyril, et al.
Publicado: (2008)

Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ
por: Bebenek, Katarzyna, et al.
Publicado: (2008)

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break
por: Kaminski, Andrea M., et al.
Publicado: (2020)

DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae
por: Hum, Yee Fang, et al.
Publicado: (2018)

Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae
por: Enserink, Jorrit M., et al.
Publicado: (2006)

Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans
por: Flood, Carrie L., et al.
Publicado: (2015)

Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5′-flaps
por: Koc, Katrina N., et al.
Publicado: (2015)

Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae
por: Casper, Anne M., et al.
Publicado: (2008)

The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases δ and η
por: McCulloch, Scott D., et al.
Publicado: (2009)

GCN5 Is a Positive Regulator of Origins of DNA Replication in Saccharomyces cerevisiae
por: Espinosa, Maria Claudia, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_5v028pmbfi427vh6h2ik0s0bno