Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications

Despite established clinical utilisation, there is an increasing need for safer, more inert gadolinium-based contrast agents, and for chelators that react rapidly with radiometals. Here we report the syntheses of a series of chiral DOTA chelators and their corresponding metal complexes and reveal pr...

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Detalles Bibliográficos
Autores principales: Dai, Lixiong, Jones, Chloe M., Chan, Wesley Ting Kwok, Pham, Tiffany A., Ling, Xiaoxi, Gale, Eric M., Rotile, Nicholas J., Tai, William Chi-Shing, Anderson, Carolyn J., Caravan, Peter, Law, Ga-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829242/
https://www.ncbi.nlm.nih.gov/pubmed/29487362
http://dx.doi.org/10.1038/s41467-018-03315-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829242/
https://www.ncbi.nlm.nih.gov/pubmed/29487362
http://dx.doi.org/10.1038/s41467-018-03315-8

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