Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation

Enteropathogenic E. coli infection is characterized by rapid onset of diarrhea but the underlying mechanisms are not well defined. EPEC targets the tight junctions which selectively regulate the permeability of charged and uncharged molecules. Cooperative actions of the EPEC effectors EspF and Map h...

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Detalles Bibliográficos
Autores principales: Singh, Anand Prakash, Sharma, Swati, Pagarware, Kirti, Siraji, Rafay Anwar, Ansari, Imran, Mandal, Anupam, Walling, Pangertoshi, Aijaz, Saima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829253/
https://www.ncbi.nlm.nih.gov/pubmed/29487356
http://dx.doi.org/10.1038/s41598-018-22017-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829253/
https://www.ncbi.nlm.nih.gov/pubmed/29487356
http://dx.doi.org/10.1038/s41598-018-22017-1

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