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Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation
Enteropathogenic E. coli infection is characterized by rapid onset of diarrhea but the underlying mechanisms are not well defined. EPEC targets the tight junctions which selectively regulate the permeability of charged and uncharged molecules. Cooperative actions of the EPEC effectors EspF and Map h...
Autores principales: | Singh, Anand Prakash, Sharma, Swati, Pagarware, Kirti, Siraji, Rafay Anwar, Ansari, Imran, Mandal, Anupam, Walling, Pangertoshi, Aijaz, Saima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829253/ https://www.ncbi.nlm.nih.gov/pubmed/29487356 http://dx.doi.org/10.1038/s41598-018-22017-1 |
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