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Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori

There is an urgent need to discover novel antimicrobial therapies. Drug repurposing can reduce the time and cost risk associated with drug development. We report the inhibitory effects of anthelmintic drugs (niclosamide, oxyclozanide, closantel, rafoxanide) against Helicobacter pylori strain 60190 a...

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Detalles Bibliográficos
Autores principales: Tharmalingam, Nagendran, Port, Jenna, Castillo, Dawilmer, Mylonakis, Eleftherios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829259/
https://www.ncbi.nlm.nih.gov/pubmed/29487357
http://dx.doi.org/10.1038/s41598-018-22037-x