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Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification

Accurately predicting cardioactive effects of new molecular entities for therapeutics remains a daunting challenge. Immense research effort has been focused toward creating new screening platforms that utilize human pluripotent stem cell (hPSC)-derived cardiomyocytes and three-dimensional engineered...

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Detalles Bibliográficos
Autores principales: Lee, Eugene K., Tran, David D., Keung, Wendy, Chan, Patrick, Wong, Gabriel, Chan, Camie W., Costa, Kevin D., Li, Ronald A., Khine, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829317/
https://www.ncbi.nlm.nih.gov/pubmed/29033305
http://dx.doi.org/10.1016/j.stemcr.2017.09.008