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Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification
Accurately predicting cardioactive effects of new molecular entities for therapeutics remains a daunting challenge. Immense research effort has been focused toward creating new screening platforms that utilize human pluripotent stem cell (hPSC)-derived cardiomyocytes and three-dimensional engineered...
Autores principales: | Lee, Eugene K., Tran, David D., Keung, Wendy, Chan, Patrick, Wong, Gabriel, Chan, Camie W., Costa, Kevin D., Li, Ronald A., Khine, Michelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829317/ https://www.ncbi.nlm.nih.gov/pubmed/29033305 http://dx.doi.org/10.1016/j.stemcr.2017.09.008 |
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