Piper retrofractum Vahl. Extract, as a PPARδ and AMPK Activator, Suppresses UVB-Induced Photoaging through Mitochondrial Biogenesis and MMPs Inhibition in Human Dermal Fibroblasts and Hairless Mice

Photoaging occurs by UVB-irradiation and involves production of reactive oxygen species (ROS) and overexpression of matrix metalloproteinases (MMPs), leading to extracellular matrix damage. Piper retrofractum Vahl. is used as a traditional medicine for antiflatulence, expectorant, sedative, and anti...

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Detalles Bibliográficos
Autores principales: Yun, Jungon, Kim, Changhee, Kim, Mi-Bo, Hwang, Jae-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829337/
https://www.ncbi.nlm.nih.gov/pubmed/29619069
http://dx.doi.org/10.1155/2018/6172954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829337/
https://www.ncbi.nlm.nih.gov/pubmed/29619069
http://dx.doi.org/10.1155/2018/6172954

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