Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

Ceramides and their metabolites are important for the homeostasis of the epidermis, but much remains unknown about the roles of specific pathways of ceramide metabolism in skin biology. With a mouse model deficient in the alkaline ceramidase (Acer1) gene, we demonstrate that ACER1 plays a key role i...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Li, Xu, Ruijuan, Yi, Jae Kyo, Li, Fang, Chen, Jiang, Jones, Evan C., Slutsky, Jordan B., Huang, Liqun, Rigas, Basil, Cao, Jian, Zhong, Xiaoming, Snider, Ashley J., Obeid, Lina M., Hannun, Yusuf A., Mao, Cungui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829345/
https://www.ncbi.nlm.nih.gov/pubmed/29056331
http://dx.doi.org/10.1016/j.stemcr.2017.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829345/
https://www.ncbi.nlm.nih.gov/pubmed/29056331
http://dx.doi.org/10.1016/j.stemcr.2017.09.015

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