Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters

This study investigated associations between SNPs in genes encoding metabolizing drug enzymes and laboratory parameters in sickle cell anemia patients under hydroxyurea (SCA-HU(+)). We evaluated hematologic and biochemical parameters by electronic methods and SNPs by PCR-RFLP and multiplex PCR in 35...

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Detalles Bibliográficos
Autores principales: Yahouédéhou, Sètondji Cocou Modeste Alexandre, Carvalho, Magda Oliveira Seixas, Oliveira, Rodrigo Mota, Santiago, Rayra Pereira, da Guarda, Caroline Conceição, Carvalho, Suellen Pinheiro, Ferreira, Júnia Raquel Dutra, Aleluia, Milena Magalhães, Adorno, Elisângela Vitória, Gonçalves, Marilda de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829363/
https://www.ncbi.nlm.nih.gov/pubmed/29619129
http://dx.doi.org/10.1155/2018/6105691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829363/
https://www.ncbi.nlm.nih.gov/pubmed/29619129
http://dx.doi.org/10.1155/2018/6105691

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