miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

Drosophila lethal giant larvae (lgl) encodes a conserved tumor suppressor with established roles in cell polarity, asymmetric division, and proliferation control. Lgl's human orthologs, HUGL1 and HUGL2, are altered in human cancers, however, its mechanistic role as a tumor suppressor remains po...

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Detalles Bibliográficos
Autores principales: Daniel, Scott G., Russ, Atlantis D., Guthridge, Kathryn M., Raina, Ammad I., Estes, Patricia S., Parsons, Linda M., Richardson, Helena E., Schroeder, Joyce A., Zarnescu, Daniela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829493/
https://www.ncbi.nlm.nih.gov/pubmed/29361610
http://dx.doi.org/10.1242/bio.027391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829493/
https://www.ncbi.nlm.nih.gov/pubmed/29361610
http://dx.doi.org/10.1242/bio.027391

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