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LIF-activated Jak signaling determines Esrrb expression during late-stage reprogramming

The regulatory process of naïve-state induced pluripotent stem cell (iPSC) generation is not well understood. Leukemia inhibitory factor (LIF)-activated Janus kinase/signal transducer and activator of transcription 3 (Jak/Stat3) is the master regulator for naïve-state pluripotency achievement and ma...

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Detalles Bibliográficos
Autores principales: Huang, Delun, Wang, Ling, Duan, Jingyue, Huang, Chang, Tian, Xiuchun (Cindy), Zhang, Ming, Tang, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829498/
https://www.ncbi.nlm.nih.gov/pubmed/29212799
http://dx.doi.org/10.1242/bio.029264