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Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Centrosomes are microtubule-nucleating organelles that facilitate chromosome segregation and cell division in metazoans. Centrosomes comprise centrioles that organize a micron-scale mass of protein called pericentriolar material (PCM) from which microtubules nucleate. During each cell cycle, PCM acc...

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Detalles Bibliográficos
Autores principales: Enos, Stephen J., Dressler, Martin, Gomes, Beatriz Ferreira, Hyman, Anthony A., Woodruff, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829501/
https://www.ncbi.nlm.nih.gov/pubmed/29222174
http://dx.doi.org/10.1242/bio.029777