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Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit
Centrosomes are microtubule-nucleating organelles that facilitate chromosome segregation and cell division in metazoans. Centrosomes comprise centrioles that organize a micron-scale mass of protein called pericentriolar material (PCM) from which microtubules nucleate. During each cell cycle, PCM acc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829501/ https://www.ncbi.nlm.nih.gov/pubmed/29222174 http://dx.doi.org/10.1242/bio.029777 |