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Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas

Amphibians provide an ideal model to study the actions of thyroid hormone (TH) in animal development because TH signaling via two TH receptors, TRα and TRβ, is indispensable for amphibian metamorphosis. However, specific roles for the TRβ isoform in metamorphosis are poorly understood. To address th...

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Detalles Bibliográficos
Autores principales: Sakane, Yuto, Iida, Midori, Hasebe, Takashi, Fujii, Satoshi, Buchholz, Daniel R., Ishizuya-Oka, Atsuko, Yamamoto, Takashi, Suzuki, Ken-ichi T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829506/
https://www.ncbi.nlm.nih.gov/pubmed/29358165
http://dx.doi.org/10.1242/bio.030338