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Niclosamide rescues microcephaly in a humanized in vivo model of Zika infection using human induced neural stem cells

Zika virus (ZIKV) is a mosquito-transmitted flavivirus with a causative link to microcephaly, a condition resulting in reduced cranial size and brain abnormalities. Despite recent progress, there is a current lack of in vivo models that permit the study of systemic virus on human neurons in a develo...

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Detalles Bibliográficos
Autores principales: Cairns, Dana M., Boorgu, Devi Sai Sri Kavya, Levin, Michael, Kaplan, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829514/
https://www.ncbi.nlm.nih.gov/pubmed/29378701
http://dx.doi.org/10.1242/bio.031807