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Niclosamide rescues microcephaly in a humanized in vivo model of Zika infection using human induced neural stem cells
Zika virus (ZIKV) is a mosquito-transmitted flavivirus with a causative link to microcephaly, a condition resulting in reduced cranial size and brain abnormalities. Despite recent progress, there is a current lack of in vivo models that permit the study of systemic virus on human neurons in a develo...
Autores principales: | Cairns, Dana M., Boorgu, Devi Sai Sri Kavya, Levin, Michael, Kaplan, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829514/ https://www.ncbi.nlm.nih.gov/pubmed/29378701 http://dx.doi.org/10.1242/bio.031807 |
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