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Preliminary Study of the Role F-Box Protein 32 (FBXO32) in Colorectal Neoplasms Through the Transforming Growth Factor beta (TGF-β)/Smad4 Signalling Pathway

BACKGROUND: F-box protein 32 (FBXO32) (also known as atrogin-1), a member of the F-box protein family, was recently shown to be a transforming growth factor beta (TGF-β)/Smad4 target gene involved in regulating cell survival. It can be transcriptionally silenced by epigenetic mechanisms in some canc...

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Detalles Bibliográficos
Autores principales: Yuan, Xuemin, Zhang, Zhen, Jiang, Kaitong, Wang, Xinguo, Li, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829536/
https://www.ncbi.nlm.nih.gov/pubmed/29465067
http://dx.doi.org/10.12659/MSM.908030