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Identification of large rearrangements in cancer genomes with barcode linked reads

Large genomic rearrangements involve inversions, deletions and other structural changes that span Megabase segments of the human genome. This category of genetic aberration is the cause of many hereditary genetic disorders and contributes to pathogenesis of diseases like cancer. We developed a new a...

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Detalles Bibliográficos
Autores principales: Xia, Li C, Bell, John M, Wood-Bouwens, Christina, Chen, Jiamin J, Zhang, Nancy R, Ji, Hanlee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829571/
https://www.ncbi.nlm.nih.gov/pubmed/29186506
http://dx.doi.org/10.1093/nar/gkx1193