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Two-step interrogation then recognition of DNA binding site by Integration Host Factor: an architectural DNA-bending protein
The dynamics and mechanism of how site-specific DNA-bending proteins initially interrogate potential binding sites prior to recognition have remained elusive for most systems. Here we present these dynamics for Integration Host factor (IHF), a nucleoid-associated architectural protein, using a μs-re...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829579/ https://www.ncbi.nlm.nih.gov/pubmed/29267885 http://dx.doi.org/10.1093/nar/gkx1215 |