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Two-step interrogation then recognition of DNA binding site by Integration Host Factor: an architectural DNA-bending protein

The dynamics and mechanism of how site-specific DNA-bending proteins initially interrogate potential binding sites prior to recognition have remained elusive for most systems. Here we present these dynamics for Integration Host factor (IHF), a nucleoid-associated architectural protein, using a μs-re...

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Detalles Bibliográficos
Autores principales:	Velmurugu, Yogambigai, Vivas, Paula, Connolly, Mitchell, Kuznetsov, Serguei V, Rice, Phoebe A, Ansari, Anjum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829579/ https://www.ncbi.nlm.nih.gov/pubmed/29267885 http://dx.doi.org/10.1093/nar/gkx1215

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