Negative regulation of B cell responses and self-tolerance to RNA-related lupus self-antigen

The antibody response to RNA-related antigens such as Sm/RNP requires the endosomal RNA sensor TLR7, and this process is crucial in the development of systemic lupus erythematosus at least in animal models. The inhibitory B cell receptor CD72 is unique because it recognizes Sm/RNP and specifically i...

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Detalles Bibliográficos
Autor principal: TSUBATA, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829613/
https://www.ncbi.nlm.nih.gov/pubmed/29321445
http://dx.doi.org/10.2183/pjab.94.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829613/
https://www.ncbi.nlm.nih.gov/pubmed/29321445
http://dx.doi.org/10.2183/pjab.94.003

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