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Negative regulation of B cell responses and self-tolerance to RNA-related lupus self-antigen
The antibody response to RNA-related antigens such as Sm/RNP requires the endosomal RNA sensor TLR7, and this process is crucial in the development of systemic lupus erythematosus at least in animal models. The inhibitory B cell receptor CD72 is unique because it recognizes Sm/RNP and specifically i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japan Academy
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829613/ https://www.ncbi.nlm.nih.gov/pubmed/29321445 http://dx.doi.org/10.2183/pjab.94.003 |