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Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition

Long interspersed nuclear element 1 is an autonomous non-long terminal repeat retrotransposon that comprises ∼17% of the human genome. Its spontaneous retrotransposition and the accumulation of heritable L1 insertions can potentially result in genome instability and sporadic disorders. Moloney leuke...

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Detalles Bibliográficos
Autores principales: Choi, Jongsu, Hwang, Sung-Yeon, Ahn, Kwangseog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829647/
https://www.ncbi.nlm.nih.gov/pubmed/29315404
http://dx.doi.org/10.1093/nar/gkx1312