Adaptive design clinical trials: a review of the literature and ClinicalTrials.gov

OBJECTIVES: This review investigates characteristics of implemented adaptive design clinical trials and provides examples of regulatory experience with such trials. DESIGN: Review of adaptive design clinical trials in EMBASE, PubMed, Cochrane Registry of Controlled Clinical Trials, Web of Science an...

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Detalles Bibliográficos
Autores principales: Bothwell, Laura E, Avorn, Jerry, Khan, Nazleen F, Kesselheim, Aaron S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Research Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829673/
https://www.ncbi.nlm.nih.gov/pubmed/29440155
http://dx.doi.org/10.1136/bmjopen-2017-018320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829673/
https://www.ncbi.nlm.nih.gov/pubmed/29440155
http://dx.doi.org/10.1136/bmjopen-2017-018320

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