Cargando…
Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse
The mouse is widely used as system to study human genetic mechanisms. However, extensive rewiring of transcriptional regulatory networks often confounds translation of findings between human and mouse. Site-specific gain and loss of individual transcription factor binding sites (TFBS) has caused fun...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829737/ https://www.ncbi.nlm.nih.gov/pubmed/29361190 http://dx.doi.org/10.1093/nar/gky018 |