DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA

Sensitive detection of the single nucleotide variants in cell-free DNA (cfDNA) may provide great opportunity for minimally invasive diagnosis and prognosis of cancer and other related diseases. Here, we demonstrate a facile new strategy for quantitative measurement of cfDNA mutations at low abundanc...

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Detalles Bibliográficos
Autores principales: Wu, Tongbo, Chen, Wei, Yang, Ziyu, Tan, Haocheng, Wang, Jiayu, Xiao, Xianjin, Li, Mengyuan, Zhao, Meiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829738/
https://www.ncbi.nlm.nih.gov/pubmed/29190359
http://dx.doi.org/10.1093/nar/gkx1218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829738/
https://www.ncbi.nlm.nih.gov/pubmed/29190359
http://dx.doi.org/10.1093/nar/gkx1218

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