Cargando…

PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing

The PolyC binding proteins (PCBPs) impact alternative splicing of a subset of mammalian genes that are enriched in basic cellular functions. Here, we focus our analysis on PCBP-controlled cassette exon-splicing within the cell cycle control regulator cyclin-dependent kinase-2 (CDK2) transcript. We d...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Xinjun, Humenik, Jesse, Yang, Daphne, Liebhaber, Stephen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829739/
https://www.ncbi.nlm.nih.gov/pubmed/29253178
http://dx.doi.org/10.1093/nar/gkx1255