Bacterial artificial chromosomes establish replication timing and sub-nuclear compartment de novo as extra-chromosomal vectors

The role of DNA sequence in determining replication timing (RT) and chromatin higher order organization remains elusive. To address this question, we have developed an extra-chromosomal replication system (E-BACs) consisting of ∼200 kb human bacterial artificial chromosomes (BACs) modified with Epst...

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Detalles Bibliográficos
Autores principales: Sima, Jiao, Bartlett, Daniel A, Gordon, Molly R, Gilbert, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829748/
https://www.ncbi.nlm.nih.gov/pubmed/29294101
http://dx.doi.org/10.1093/nar/gkx1265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829748/
https://www.ncbi.nlm.nih.gov/pubmed/29294101
http://dx.doi.org/10.1093/nar/gkx1265

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