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Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family

Bordetella pertussis controls the expression of its virulence regulon through the two-component system BvgAS. BvgS is a prototype for a family of multidomain sensor kinases. In BvgS, helical linkers connect periplasmic Venus flytrap (VFT) perception domains to a cytoplasmic Per-Arnt-Sim (PAS) domain...

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Detalles Bibliográficos
Autores principales: Lesne, Elodie, Dupré, Elian, Lensink, Marc F., Locht, Camille, Antoine, Rudy, Jacob-Dubuisson, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829827/
https://www.ncbi.nlm.nih.gov/pubmed/29487240
http://dx.doi.org/10.1128/mBio.02052-17