Evaluating the impact of type 2 diabetes mellitus on CYP450 metabolic activities: protocol for a case–control pharmacokinetic study

INTRODUCTION: Diabetes affects more than 9% of the adult population worldwide. Patients with type 2 diabetes mellitus (T2DM) show variable responses to some drugs which may be due, in part, to variability in the functional activity of drug-metabolising enzymes including cytochromes P450 (CYP450s). C...

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Detalles Bibliográficos
Autores principales: Gravel, Sophie, Chiasson, Jean-Louis, Dallaire, Suzanne, Turgeon, Jacques, Michaud, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Diabetes and Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829905/
https://www.ncbi.nlm.nih.gov/pubmed/29439084
http://dx.doi.org/10.1136/bmjopen-2017-020922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829905/
https://www.ncbi.nlm.nih.gov/pubmed/29439084
http://dx.doi.org/10.1136/bmjopen-2017-020922

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