Cargando…

ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response

Activation of the unfolded protein response (UPR) sustains protein homeostasis (proteostasis) and plays a fundamental role in tissue maintenance and longevity of organisms. Long-range control of UPR activation has been demonstrated in invertebrates, but such mechanisms in mammals remain elusive. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Chapple, Richard H, Hu, Tianyuan, Tseng, Yu-Jung, Liu, Lu, Kitano, Ayumi, Luu, Victor, Hoegenauer, Kevin A, Iwawaki, Takao, Li, Qing, Nakada, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829925/
https://www.ncbi.nlm.nih.gov/pubmed/29451493
http://dx.doi.org/10.7554/eLife.31159